Antidepressants associated with infant withdrawal syndrome

NEWS IN BRIEF — Posted Feb. 28, 2005

Print  |   Email  |   Respond  |   Reprints  |   Like Facebook  |   Share Twitter  |   Tweet Linkedin

The use of selective serotonin reuptake inhibitors by pregnant women is linked to the development of drug-related withdrawal symptoms in newborns, according to a study published in the Feb. 5 issue of The Lancet.

Researchers at the University of La Laguna in Tenerife, Spain, analyzed World Health Organization adverse drug reaction data collected from 72 countries. A total of 93 suspected cases of neonatal withdrawal syndrome were linked to the use of these drugs with 63 associated with paroxetine (Paxil). Thirteen were linked to fluoxetine (Prozac), and one case was associated with using both paroxetine and fluoxetine. Nine were connected to sertraline (Zoloft), and citalopram (Celexa), was linked to seven cases.

The authors suggested that pregnant women using these drugs, particularly paroxetine, should be monitored closely, and an accompanying commentary by researchers at Yale University in New Haven, Conn., warned against abrupt discontinuation.

"A precipitous shift away from widespread prescription of SSRIs is not called for and would do much more damage than good," the authors wrote.

Note: This item originally appeared at

Back to top



Read story

Confronting bias against obese patients

Medical educators are starting to raise awareness about how weight-related stigma can impair patient-physician communication and the treatment of obesity. Read story

Read story


American Medical News is ceasing publication after 55 years of serving physicians by keeping them informed of their rapidly changing profession. Read story

Read story

Policing medical practice employees after work

Doctors can try to regulate staff actions outside the office, but they must watch what they try to stamp out and how they do it. Read story

Read story

Diabetes prevention: Set on a course for lifestyle change

The YMCA's evidence-based program is helping prediabetic patients eat right, get active and lose weight. Read story

Read story

Medicaid's muddled preventive care picture

The health system reform law promises no-cost coverage of a lengthy list of screenings and other prevention services, but some beneficiaries still might miss out. Read story

Read story

How to get tax breaks for your medical practice

Federal, state and local governments offer doctors incentives because practices are recognized as economic engines. But physicians must know how and where to find them. Read story

Read story

Advance pay ACOs: A down payment on Medicare's future

Accountable care organizations that pay doctors up-front bring practice improvements, but it's unclear yet if program actuaries will see a return on investment. Read story

Read story

Physician liability: Your team, your legal risk

When health care team members drop the ball, it's often doctors who end up in court. How can physicians improve such care and avoid risks? Read story

  • Stay informed
  • Twitter
  • Facebook
  • RSS
  • LinkedIn