Health
Herpes linked to widespread neuropathic pain
NEWS IN BRIEF — Posted Aug. 18, 2008
Those at increased risk for herpes flare-ups also are more likely to experience significant pain on one side of their bodies during outbreaks, according to a paper in the July Journal of Pain.
Researchers at the University of Helsinki in Finland analyzed serum samples and skin biopsies of 17 patients who tested positive for herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) and reported widespread pain. They found that those with low immunoglobulin levels and certain versions of several genes regulating the immune system were at increased risk for this syndrome. Patients received relief when they took medications addressing the herpes infection.
The authors suggest that herpes reactivation may trigger an inflammatory process disrupting the central nervous system and causing pain. They are calling for additional research using functional brain imaging to further clarify this condition.
Note: This item originally appeared at http://www.ama-assn.org/amednews/2008/08/18/hlbf0818.htm.
