New research aims to treat sinusitis

NEWS IN BRIEF — Posted Aug. 25, 2008

Print  |   Email  |   Respond  |   Reprints  |   Like Facebook  |   Share Twitter  |   Tweet Linkedin

Newly developed genetically engineered mice with inflamed nasal tissues are expected to aid in the development of treatments for chronic sinusitis, a condition that affects an estimated 31 million Americans.

"Until now, the lack of realistic animal models for each of the key symptoms of chronic inflammation in the nasal tissue -- such as the growth of nasal polyps, the loss of the sense of smell, swollen sinus tissue or clogged and runny noses -- has slowed sinusitis research and hindered our search for therapies," said Andrew Lane, MD, an associate professor at the Johns Hopkins University School of Medicine in Baltimore, who led the team of researchers that developed the mice.

He introduced them July 22 at the XV International Symposium on Olfaction and Taste being held in San Francisco.

New therapies are needed, Dr. Lane said, as an alternative to long-term steroids, which block the inflammatory chemical pathway but also have debilitating side effects, such as loss of bone density, cataracts and weight gain.

Note: This item originally appeared at

Back to top



Read story

Confronting bias against obese patients

Medical educators are starting to raise awareness about how weight-related stigma can impair patient-physician communication and the treatment of obesity. Read story

Read story


American Medical News is ceasing publication after 55 years of serving physicians by keeping them informed of their rapidly changing profession. Read story

Read story

Policing medical practice employees after work

Doctors can try to regulate staff actions outside the office, but they must watch what they try to stamp out and how they do it. Read story

Read story

Diabetes prevention: Set on a course for lifestyle change

The YMCA's evidence-based program is helping prediabetic patients eat right, get active and lose weight. Read story

Read story

Medicaid's muddled preventive care picture

The health system reform law promises no-cost coverage of a lengthy list of screenings and other prevention services, but some beneficiaries still might miss out. Read story

Read story

How to get tax breaks for your medical practice

Federal, state and local governments offer doctors incentives because practices are recognized as economic engines. But physicians must know how and where to find them. Read story

Read story

Advance pay ACOs: A down payment on Medicare's future

Accountable care organizations that pay doctors up-front bring practice improvements, but it's unclear yet if program actuaries will see a return on investment. Read story

Read story

Physician liability: Your team, your legal risk

When health care team members drop the ball, it's often doctors who end up in court. How can physicians improve such care and avoid risks? Read story

  • Stay informed
  • Twitter
  • Facebook
  • RSS
  • LinkedIn