Boosting HDL may not be enough to prevent heart disease

NEWS IN BRIEF — Posted Sept. 10, 2007

Print  |   Email  |   Respond  |   Reprints  |   Like Facebook  |   Share Twitter  |   Tweet Linkedin

While it's known as the good cholesterol, recent research has found that HDL isn't always on the bright side. It may be that simply boosting HDL levels is not sufficient to prevent heart disease, said the researchers who presented their findings Aug. 22 at the American Chemical Society's national meeting in Boston.

In an analysis of the protein composition of HDL, researchers from the University of Washington School of Medicine in Seattle found 48 proteins, including 22 that play a role in cholesterol metabolism and 13 not previously known to exist in HDL.

Scientists have long suspected that there may be dysfunctional forms of HDL cholesterol that aren't heart protective. But the chemical composition of this cholesterol had been unknown.

A promising study designed to boost HDL levels was recently halted when it was found that the drug being tested caused an increase in deaths and heart problems.

Note: This item originally appeared at

Back to top



Read story

Confronting bias against obese patients

Medical educators are starting to raise awareness about how weight-related stigma can impair patient-physician communication and the treatment of obesity. Read story

Read story


American Medical News is ceasing publication after 55 years of serving physicians by keeping them informed of their rapidly changing profession. Read story

Read story

Policing medical practice employees after work

Doctors can try to regulate staff actions outside the office, but they must watch what they try to stamp out and how they do it. Read story

Read story

Diabetes prevention: Set on a course for lifestyle change

The YMCA's evidence-based program is helping prediabetic patients eat right, get active and lose weight. Read story

Read story

Medicaid's muddled preventive care picture

The health system reform law promises no-cost coverage of a lengthy list of screenings and other prevention services, but some beneficiaries still might miss out. Read story

Read story

How to get tax breaks for your medical practice

Federal, state and local governments offer doctors incentives because practices are recognized as economic engines. But physicians must know how and where to find them. Read story

Read story

Advance pay ACOs: A down payment on Medicare's future

Accountable care organizations that pay doctors up-front bring practice improvements, but it's unclear yet if program actuaries will see a return on investment. Read story

Read story

Physician liability: Your team, your legal risk

When health care team members drop the ball, it's often doctors who end up in court. How can physicians improve such care and avoid risks? Read story

  • Stay informed
  • Twitter
  • Facebook
  • RSS
  • LinkedIn